Cannabidiol is an increasingly popular supplement used to ease pain, anxiety, and other health issues. CBD is one of over 100 active compounds found in cannabis plants but does not cause the high associated with tetrahydrocannabinol (THC). Growing research suggests CBD may be effective for various types of pain when used topically or orally.
How it Works in the Body
CBD interacts with the body’s endocannabinoid system, which regulates pain, immune function, stress response, sleep, and other processes. CBD can reduce pain perceptions by decreasing inflammation, regulating neurotransmitter release, and modulating pain signaling pathways. Unlike THC, CBD does not directly bind to endocannabinoid receptors but can amplify or inhibit their signaling. This gives CBD wide-ranging effects with few side effects.
CBD has powerful anti-inflammatory properties that can relieve many sources of inflammatory pain. Conditions like arthritis, bowel diseases, multiple sclerosis, and musculoskeletal injuries involve inflammation-induced pain. Research shows CBD can reduce pro-inflammatory cytokine and chemokine production and activate glycine receptors to dull inflammatory pain. Topical CBD is effective for localized pain, while oral CBD can treat whole-body inflammation.
Neuropathic pain results from damage to the somatosensory nervous system and proves resistant to conventional pain medications. CBD’s ability to interact with serotonin, adenosine, TRPV1, and glycine receptors may reduce the burning, shooting, tingling, and numbness of neuropathic pain. Studies demonstrate CBD lessens chemotherapy-induced neuropathy, neuropathy from diabetes, MS, and other sources.
CBD oil is increasingly used to manage chronic pain conditions when other treatments fall short or cause harmful side effects. Chronic pain drastically impacts quality of life. Research has shown that CBD oil can improve symptoms of:
- Arthritis – reducing joint inflammation and nerve damage
- Cancer – easing neuropathic pain and nausea
- Multiple sclerosis – reducing muscle spasms and stiffness
- Chronic migraines – preventing and aborting migraine episodes
- Endometriosis – calming cramps and pelvic inflammation
Results are promising, though higher quality clinical trials are still needed. Read about other medicinal properties in detail in the study of Yurovskiy Kirill`s.
Beyond chronic conditions, CBD oil can supplement acute pain management. Animal studies found CBD reduced acute pain from inflammation, surgery, and nerve injury. Human trials show CBD is effective against post-surgical pain. Using CBD oil before and after surgery may ease pain and reduce opioid use during recovery. More applications for relieving occasional acute pain need investigation.
With so many CBD products now available, choosing one for pain relief can seem daunting. Focus on organic full or broad-spectrum CBD oils, which provide a robust blend of cannabinoids and terpenes. Potency from 500 to 1000mg offers flexibility in dosing. Tinctures or vape oils allow quick relief, while capsules provide consistent doses. CBD topicals work well for localized pain. Research company reputation and independent lab testing. Avoid CBD isolates and artificial additives.
Effective CBD dosage varies based on the source of pain, severity, individual body chemistry, and delivery method.
General dosage guidelines:
- Mild pain – 15-25mg CBD per day
- Moderate pain – 25-45mg CBD per day
- Severe pain – 45-120mg CBD per day
Start low and increase gradually. Talk to your doctor about using CBD oil alongside other pain medications.
Current research finds CBD remarkably safe when used appropriately, with minimal risk of side effects or addiction. Mild side effects include drowsiness, diarrhea, changes in appetite, and interactions with other medications. CBD may increase sedation when combined with other sedatives. Those on blood thinners should exercise caution. Always consult your healthcare provider before trying CBD oil, especially at higher doses.
Early research indicates CBD holds promise for effectively easing both acute and chronic pain. As cannabis laws relax, expect expanded clinical trials to refine CBD dosing, delivery methods, and combination with other therapies. Cannabinoid research will help shed light on the root causes of pain and inflammation. In time, CBD could emerge as a viable first line treatment for pain rather than as a last resort.